Merrill Cook

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  • What databases can Balto query?

    PDB (Protein Data Bank)UniProtAlphaFoldChEMBLBindingDBPubChemOpen Targets

  • What molecular properties can Balto predict?

    Aqueous solubility (LogS)Lipophilicity (LogP, LogD)hERG inhibition likelihoodCYP450 interaction likelihoodAmes mutagenicity likelihoodMolecular weight (MW)Protonation stateSynthetic Accessibility S...

  • What algorithms does Balto use?

    Balto integrates Deep Origin’s proprietary algorithms for docking, property predictions, and pocket identification. It also utilizes publicly available tools and databases such as MolStar, PDB, ChE...

  • What molecular modeling tasks can Balto perform?

    Molecular Docking: DO Dock (proprietary algorithm for rigid docking within the assigned docking grid)Molecular Property Predictions: LogP, LogD, LogS, hERG, CYP, Ames, QED, SASBinding Pocket Identi...

  • What does Balto do?

    Balto simplifies drug discovery by making information and molecular modeling more accessible:AI-Guided Conversations: Perform complex molecular modeling tasks through natural language interactionsM...

  • How do I start using Balto?

    Use sample prompts for common tasks to get familiar with Balto communication style. You are also welcome to explore Balto at your own pace by just entering a prompt in a chat window. 

  • Does Balto ever provide incorrect information?

    Although Balto’s responses are highly reliable, occasional inaccuracies (hallucinations) may occur. We recommend verifying critical information independently.

  • Why is it called Balto?

    Balto is named after the heroic sled dog famous for his 1925 emergency run delivering diphtheria antivenom to Nome, Alaska. Our goal is for Balto to be just as invaluable in advancing drug discover...

  • Does Balto work on a Mobile device?

    Yes, Balto is supported on mobile devices. However, visualizations work better in larger screens.

  • How much does it cost to use Balto?

    Subscription is FREE. The majority of Balto actions are FREE, as well. However, Balto does charge per action for some computationally intensive tools (e.g., docking) beyond the monthly quota. See P...